Why Choose Needleless Rejuran?
Needleless Rejuran provides the clinical benefits of Rejuran polynucleotides: without the pain and downtime of injections. Using needle-free transdermal technologies, it delivers PN molecules comfortably and evenly, making Rejuran more accessible for patients who prefer a non-invasive approach.
What Is Needleless Rejuran?
Needleless Rejuran is a transdermal delivery approach that allows Rejuran’s bioactive polynucleotides (PN) to penetrate the skin without injections. Instead of microinjections, PN molecules are introduced using:
- Ultrasound permeation, commonly used to assist transdermal delivery of topical agents
- Iontophoresis, which uses controlled microcurrent to support movement of molecules across the skin
- Derma Electroporation (DEP), a technique that applies electrical pulses to facilitate transdermal application
- High-velocity fine mist / jet technology designed for uniform surface deposition of polynucleotides
These technologies allow PN to reach targeted skin layers non-invasively, supporting collagen repair, barrier recovery, and hydration improvement — with no downtime.
Why the Needleless Rejuran Approach Matters
Traditional Rejuran involves injections, which can produce temporary visible bumps and discomfort. For many patients, the fear of pain or being unable to accommodate visible downtime because of work,cause them to reduce treatment consistency, which is essential for optimal PN outcomes. Needleless Rejuran removes these barriers while maintaining the therapeutic value of polynucleotides.
No Injection Marks or Downtime
No papules, bumps, or post-procedure redness. Patients can immediately resume work or social activity.
Comfortable and Non-Invasive
Needle-free delivery is suitable for individuals with low pain tolerance or sensitivity to injections.
Better Treatment Consistency
Patients are more likely to complete the recommended Rejuran course when the process is comfortable and convenient.
Steady Collagen Repair Over Time
Consistent PN exposure supports smoother textural improvement, hydration balance, and cumulative collagen stimulation.
Who Benefits Most from Needleless Rejuran?
- Patients hesitant about injections or post-injection bumps
- Individuals seeking regular PN maintenance without downtime
- Those with sensitive or redness-prone skin
- Patients with public-facing roles who prefer no visible marks
Needleless Rejuran also serves as an excellent maintenance booster between traditional Rejuran injections, helping sustain skin repair, hydration, and collagen activity.
Discover Needleless Rejuran
Experience clinically effective PN repair with no needles and no downtime. Our doctors can recommend whether needle-free Rejuran is appropriate for your skin.
Book a ConsultationFrequently Asked Questions about Needleless Rejuran
How is Needleless Rejuran administered?
It is performed using needle-free devices such as ultrasound permeation, iontophoresis, derma electroporation (DEP), or high-velocity jet application. These methods are designed to support transdermal application of topical PN solutions.
Is there downtime after Needleless Rejuran?
Because no needles are used, visible marks associated with injections are typically not present. Individual responses may vary depending on skin condition and sensitivity.
Who may consider Needleless Rejuran?
It may be considered by individuals who prefer non-invasive options, those who wish to avoid visible downtime, or patients who are sensitive to needle-based procedures. Suitability is assessed during consultation.
Can Needleless Rejuran be done together with other procedures?
Yes you can pair transdermal PN application with other non-invasive treatments such as Pico Laser, HIFU etc. The choice of combintation treatments depends on individual skin condition and goals which will be assessed by our doctor during the consultation.
Does everyone respond the same way to Needleless Rejuran?
No. Responses may vary due to differences in skin characteristics, sensitivity, and treatment intervals. Our doctor will provide personalised guidance based on your skin assessment.
What should I expect during the consultation?
Consultation typically includes a review of your skin type, sensitivity levels, lifestyle constraints regarding downtime, and discussion of whether needle-free or injection-based PN application is appropriate for you.
How is the consultation at ClearSK like?

Assessment
Our doctors will discuss with you to understand your concerns and analyze how the treatment can help you specifically. Supported by past records and examples.

Customization
Our doctors will give you a customized plan according to your needs. This includes the target area, the recommended number of session and the number of injections needed.

After-care planning
Our doctors will advise you on the after-care following the treatment.
Meet Our Doctors

Dr Shiau Ee Leng
Dr Shiau Ee Leng has been an Aesthetic-LASER Physician since 2000. She is also trained in advanced Anti-wrinkle Injectable treatments, advanced Fillers, as well as Sculptra Rejuvenating Techniques. Dr Shiau is often invited to speak at Seminars and Conferences to help create more awareness in the aesthetics field. Her well-rounded training and years of experience in medical aesthetics has positioned her as the professional to look for to perfect your skin and body.

Dr Chen Yi Ming
Dr Chen has 15 years of experience in primary care and aesthetic treatment. He used to work in various hospitals in Singapore during his formative years, rotating through many surgical and medical departments including emergency departments and has accumulated experience in various disciplines. To date, he has performed many treatments, including chemical peels, both ablative & non-ablative lasers, non-surgical face lift.

Dr Priscilla Wang
Dr Priscilla attained her Bachelor of Medicine and Bachelor of Surgery from the renowned University of Melbourne and also completed Bachelor of Medical Science where she developed her keen interest in biomedical research. On top of being skilled at treatments such as skinboosters, subcision, threads, and ultrasound, Dr. Priscilla is further accredited by the Aesthetic Dermatology Educational Group (ADEG) to perform filler injections, Anti-wrinkle injections, lasers, intense pulsed light, and chemical peels.

Dr Melissa Chan
Dr. Melissa Chan graduated from Duke-NUS Medical School and has clinical experience across several hospitals in Singapore. She is accredited in various aesthetic procedures and is a member of the American Academy of Aesthetic Medicine. With published work in medical journals, she values evidence-based care and focuses on helping patients achieve their aesthetic goals with a natural, refined approach.

Dr Tan Yu Xiang
Dr. Tan Yu Xiang holds an M.B.B.S. from the National University of Singapore and is certified in aesthetic procedures including lasers, anti-wrinkle injections, fillers, peels, and energy-based devices. He adopts an evidence-based approach to skincare and stays updated with advancements in aesthetic medicine. Trained further by the American Academy of Aesthetic Medicine, Dr. Tan focuses on creating personalized treatment plans tailored to each patient's needs.

Dr Samantha Sim
Dr. Samantha Sim graduated from Duke-NUS Medical School and holds a Postgraduate Diploma in Surgery (MRCS England). With a background in various surgical specialties, she brings precision to aesthetic treatments with a focus on enhancing natural features. Outside of medicine, she is a trained guzheng performer, blending creativity and artistry into her approach to aesthetics.

Dr Charles
Dr. Charles is a certified medical doctor with experience in light/laser, radiofrequency, and injectable aesthetic treatments. He focuses on personalised care, aiming to help patients enhance their natural appearance through tailored treatment plans. Dedicated to continuous learning, he keeps up with new techniques to improve patient outcomes.