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ToggleCan Rejuran Skin Booster (DEP) and RF Microneedling Be Considered Together for Pores and Uneven Texture?
Quick summary: Dull, dehydrated-looking skin and visibly enlarged pores or uneven surface texture may occur at the same time, but they don’t necessarily involve the same underlying skin concerns. Where more than one concern is identified during a doctor consultation, Rejuran Skin Booster (DEP), RF Microneedling, or a combination of treatment approaches may be discussed. Whether one treatment or more than one treatment is appropriate depends on the individual’s assessment.
Rejuran Skin Booster (DEP) vs RF Microneedling: A Quick Comparison
| Rejuran Skin Booster (DEP) | RF Microneedling | |
|---|---|---|
| Downtime | Minimal to none | Minimal to none |
| Who it suits best | Those with skin quality concerns, dull-looking skin, or dehydration | Those with enlarged pores or uneven surface texture, including post-acne texture |
| Pain level | Minimal, non-injection delivery | Mild, may be eased with numbing cream |
| Results-onset speed | Gradually, across a series of sessions | Gradually, across 3–6 sessions |
| Longevity | Effects may be supported with periodic follow-up sessions | Effects may be supported with periodic follow-up sessions |
| Cost per month of result | Varies by number of sessions; a personalised quote is provided at consultation | Varies by number of sessions; a personalised quote is provided at consultation |
Disclaimer: this table is a general guide only, not a guarantee. Outcomes vary from person to person, and whether these treatments are combined depends entirely on an individual assessment by a doctor.
More Than One Skin Concern Can Be Discussed During a Consultation
People often attend a consultation with one main concern, such as dull-looking skin or visibly enlarged pores. During assessment, other skin concerns may also be identified. These concerns don’t necessarily involve the same layer of the skin or the same treatment approach.
Where more than one concern is identified, a doctor may discuss whether one treatment approach or more than one treatment category is appropriate for the individual’s skin concerns and treatment priorities.
What Role May Rejuran Skin Booster (DEP) Play Within a Treatment Plan?
Rejuran Skin Booster (DEP) (a salmon-DNA-derived skin booster) is a Korean-developed cosmetic treatment built around PDRN (Polydeoxyribonucleotide) and amino acids, delivered topically through dermo-electroporation (DEP) — a non-injection method that uses gentle electrical pulses to help the formula penetrate the skin’s surface layers. It is designed to work alongside the skin’s own surface renewal processes.
Depending on the individual’s assessment, it may be considered where concerns include:
- Skin quality
- Dull-looking skin
- Dehydration
- Overall skin radiance
Whether Rejuran Skin Booster (DEP) is appropriate depends on the individual’s skin concerns and clinical assessment.
What Role May RF Microneedling Play Within a Treatment Plan?
RF Microneedling combines microneedling with radiofrequency energy and is designed to target deeper layers of the skin, where it may support the skin’s own texture-remodelling response.
Depending on the individual’s assessment, it may be considered where concerns include:
- Enlarged or visible pores
- Uneven surface texture, including texture linked to past acne
- Rough or coarse-feeling skin
Whether RF Microneedling is appropriate depends on the individual’s skin concerns and clinical assessment.
A note on scope: RF Microneedling is also sometimes discussed in the context of early fine lines and firmness loss — a different concern from pore size and surface texture, and one covered separately. This article focuses specifically on pore and texture-related concerns rather than firmness or early collagen-related fine lines.
When Might Both Treatment Approaches Be Discussed?
Where skin quality and pore or texture concerns are both identified during assessment, a doctor may discuss whether Rejuran Skin Booster (DEP) and RF Microneedling are appropriate as part of the same overall treatment plan.
This doesn’t mean both treatments are appropriate for everyone. Some people may only require one treatment approach, while others may be considered for a combination treatment plan. The decision depends on the individual’s assessment rather than a standard treatment pathway.
Combined Plan: Rejuran Skin Booster (DEP) + RF Microneedling
| Rejuran Skin Booster (DEP) + RF Microneedling | |
|---|---|
| Downtime | Minimal to none for both |
| Who it suits best | Those with concerns spanning both skin quality (dullness, dehydration) and pore size or surface texture |
| Pain level | Minimal for the skin booster; mild for RF Microneedling, may be eased with numbing cream |
| Results-onset speed | Both build gradually, across their own respective course of sessions |
| Longevity | Both may be supported with periodic follow-up sessions |
| Cost per month of result | Varies by number of sessions for each treatment; a personalised quote is provided at consultation |
Disclaimer: this table is a general guide only, not a guarantee. Outcomes vary from person to person, and whether these treatments are combined depends entirely on an individual assessment by a doctor.
Questions About This Pairing
The Right Starting Point Is a Conversation With a Doctor
If you’ve been considering a Rejuran Skin Booster (DEP), RF Microneedling, or both, the most useful next step is a face-to-face consultation with a doctor who can assess your individual concerns and advise accordingly.
At ClearSK, our doctors take time to understand each patient’s skin condition before recommending any treatment. There is no one-size-fits-all plan – what matters is what is clinically relevant for you.
Why Patients Choose ClearSK
- 17+ years trusted in Singapore
- Thousands of treatments performed across our network of Singapore clinics
- 100+ treatment selections across skin, face, body and hair growth
- Doctor-designed protocols — treatment plans are developed and overseen by registered medical practitioners
- Multiple clinic locations across Singapore, with consistent clinical standards at each
ClearSK offers both regenerative and texture-remodelling skin treatments, so patients weighing more than one approach can be assessed across the full range of clinically appropriate options.
Where Should You Start?
- Mainly concerned about dullness or skin quality? A Rejuran Skin Booster (DEP) may be considered as part of a clinical discussion.
- Mainly concerned about enlarged pores or uneven texture? RF Microneedling may be considered depending on your clinical assessment.
- Concerns spanning both? A consultation can help determine whether a combined plan is appropriate for you.










